From: Effect of gastrointestinal resection on sunitinib exposure in patients with GIST
Major gastrectomy (n = 45) | Partial gastrectomy (n = 58 ) | Small bowel resection (n = 118) | Combination of gastrectomy and small bowel resection (n = 8 ) | Colon resection (n = 13) | Controls (n = 63) | |
---|---|---|---|---|---|---|
Sex, n (%) | ||||||
Male | 30 (66.7%) | 35 (60.3%) | 75 (63.6%) | 6 (75%) | 9 (69.2%) | 40 (63.5%) |
Female | 15 (33.3%) | 23 (39.7%) | 43 (36.4%) | 2 (25%) | 4 (30.8%) | 23 (36.5%) |
Age (years)* | 56 (36–77) | 57 (28–79) | 53 (23–81) | 49 (45–54) | 68 (50–84) | 58 (36–84) |
Bodyweight (kg)* | 65 (40–100) | 70 (39–121) | 71 (40–140) | 64 (45–139) | 80 (56–114) | 74 (44–137) |
Race, n (%) | ||||||
Non-Asian | 37 (82.2%) | 52 (89.7%) | 94 (79.7%) | 7 (87.5%) | 12 (92.3%) | 59 (93.7%) |
Asian | 8 (17.8%) | 6 (10.3%) | 24 (20.3%) | 1 (12.5%) | 1 (7.7%) | 4 (6.3%) |
ECOG performing status, n (%) | ||||||
≤ 1 | 42 (93.3%) | 58 (100%) | 116 (98.3%) | 8 (100%) | 13 (100%) | 62 (98.4%) |
≥ 2 | 3 (6.7%) | 0 (0%) | 2 (1.7%) | 0 (0%) | 0 (0%) | 1 (1.6%) |