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Table 2 Univariate and multivariate analyses of prognostic parameters for survival in patients with pancreatic ductal adenocarcinoma (PDAC)

From: Overexpression of GOLPH3 is associated with poor prognosis and clinical progression in pancreatic ductal adenocarcinoma

 

Univariate analysis

Multivariate analysis

Prognostic parameter

 

95% CI

  

95% CI

 
 

RR

Lower

Upper

Pvalue

RR

Lower

Upper

Pvalue

Expression of GOLPH3 (low vs. high)

1.915

1.186

3.092

0.008*

2.733

1.578

4.732

0.000*

Gender (male vs. female)

0.977

0.643

1.484

0.913

1.008

0.647

1.571

0.972

Age (<61 vs. ≥61)

1.295

0.865

1.938

0.209

1.319

0.840

2.073

0.229

Tumor location (head vs. body/tail)

0.882

0.521

1.493

0.640

0.619

0.349

1.100

0.102

Pathologic differentiation (well vs. moderate/poor)

1.402

0.610

3.223

0.426

0.760

0.308

1.874

0.760

Size (≤2 cm vs. >2 cm)

1.940

1.095

3.437

0.023*

1.557

0.841

2.883

0.159

T classification (T1 vs. T2 vs. T3 vs. T4)

1.187

0.941

1.496

0.148

1.001

0.658

1.521

0.998

N classification (absent vs. present)

1.075

0.718

1.611

0.725

0.608

0.386

0.957

0.032*

Liver metastasis (absent vs. present)

1.288

0.779

2.130

0.324

1.002

0.319

3.152

0.997

Clinical stage (I vs. II vs. III vs. IV)

1.243

1.014

1.523

0.036*

1.420

0.776

2.598

0.255

Treatment (radical vs. palliative)

2.444

1.609

3.710

0.000*

2.828

1.745

4.584

0.000*

  1. Univariate analysis and multivariate analyses were analyzed by Cox regression.
  2. *Statistically significant; RR: Relative Risk; 95% CI: 95% confidence interval.