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Table 5 Univariate and multivariate analyses of the prognostic factors for 5-year DFS of CRC patients (n = 292)

From: Expression of A disintegrin and metalloprotease 8 is associated with cell growth and poor survival in colorectal cancer

Indicator

Univariate analysis

Multivariate analysis

5-year DFS

p value

HR

95% CI

p value

N stage

     

  N0

68%

0.031

  

NS

  N1-N2

59%

    

Grade

     

  Well

71%

0.003

  

NS

  Moderately

57%

    

  Poorly

46%

    

TNM stage

     

  I

85%

0.017

1

Reference

0.027

  II

72%

 

2.445

0.958-6.236

 

  III

61%

 

2.482

0.954-6.457

 

CEA(ug/L)

     

  ≤5

75%

<0.0001

1

Reference

0.001

  >5

52%

 

2.052

1.342-3.145

 

CA19-9 (ug/L)

     

  ≤60

69%

0.016

  

NS

  >60

55%

    

ADAM8 protein

     

  Negative

81%

0.014

1

Reference

0.025

  Positive

67%

 

2.108

1.922-3.480

 
  1. CRC, colorectal cancer; HR, hazard ratio; CI, confidence interval; NS, not significant.