Clinical and prognostic significance of preoperative plasma hyperfibrinogenemia in gallbladder cancer patients following surgical resection: a retrospective and in vitro study

Table 5 Multivariate analysis for overall survival in GBC patients

Variables	OS HR (95% CI)	p value
TNM stage	17.42 (1.71, 177.56)	0.016
0-I vs. II-IV	17.42 (1.71, 177.56)	0.016
Lymph node metastasis	2.15 (1.06, 4.40)	0.035
Absent and not available vs. Present	2.15 (1.06, 4.40)	0.035
Fibrinogen	0.52 (0.29, 0.94)	0.031
≤402 mg/dL vs. >402 mg/dL	0.52 (0.29, 0.94)	0.031
Margin status	0.15 (0.07, 0.31)	<0.001
R0 vs. R1

GBC, gallbladder carcinoma; OS. overall survival; HR, hazard ratio; CI, confidence interval.

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