| |
Full model
|
Reduced model
|
|---|
|
Covariate
|
HR
|
95% CI
|
P-value
|
HR
|
95% CI
|
P-value
|
|---|
|
Age (70:45)
|
1.66
|
1.16-2.38
|
0.004*
|
1.70
|
1.19-2.45
|
0.002*
|
|
Sex
| | | | | | |
|
Male
|
1
| | |
-
| | |
|
Female
|
1.37
|
0.89-2.11
|
0.15
|
-
|
-
|
-
|
|
Race
| | | | | | |
|
White
|
1
| | |
-
| | |
|
Non White
|
0.80
|
0.47-1.38
|
0.42
|
-
|
-
|
-
|
|
Year of diagnosis (2000:1990)
|
0.80
|
0.61-1.05
|
0.11
|
-
|
-
|
-
|
|
Stage
| | | | | | |
|
Localized
|
1
| | |
1
| | |
|
Regional
|
2.93
|
1.43-6.00
|
0.003*
|
2.93
|
1.43-5.99
|
0.003*
|
|
Distant
|
4.88
|
2.20-10.82
|
<0.001*
|
4.82
|
2.17-10.69
|
<0.001*
|
|
Radiation
| | | | | | |
|
No
|
1
| | |
1
| | |
|
Yes
|
1.84
|
1.07-3.15
|
0.03*
|
2.14
|
1.28-3.58
|
0.004*
|
|
Histological types#
|
-
|
-
|
0.003*
|
-
|
-
|
0.004*
|
|
Surgery#
|
-
|
-
|
0.06
|
-
|
-
|
0.05
|
|
Histology × surgery
|
-
|
-
|
0.03*
|
-
|
-
|
0.02*
|
|
Surgery
| | | | | | |
|
Squamous cell carcinoma
|
1
| | |
1
| | |
|
Adenocarcinoma
|
0.16
|
0.06-0.46
|
<0.001*
|
0.18
|
0.06-0.50
|
0.001*
|
|
Others
|
0.55
|
0.27-1.12
|
0.10
|
0.60
|
0.30-1.19
|
0.15
|
|
No surgery
| | | | | | |
|
Squamous cell carcinoma
|
1
| | |
1
| | |
|
Adenocarcinoma
|
1.95
|
0.40-9.51
|
0.41
|
2.33
|
0.47-11.68
|
0.30
|
|
Others
|
0.51
|
0.19-1.39
|
0.19
|
0.54
|
0.20-1.46
|
0.22
|
-
Abbreviations: HR Hazard Ratio, CI Confidence Interval.
-
#Hazard ratios for histology type are presented by surgery because of the significant interaction between these two covariates.
- *P <0.05.
