Drug | IC50(μM) |
---|
CEM | CEM/ara-G | RR |
---|
Ara-G | 2.6 | 180 | (70) |
F-ara-A | 0.10 | 4.80 | (48) |
Ara-C | 0.15 | 0.75 | (5) |
- CEM and CEM/ara-G cells were incubated for 72Â h with various concentrations of ara-G, ara-C, or F-ara-A. The IC50 was then determined by using the XTT assay. The number in the parenthesis is the relative resistance (RR), which was obtained by dividing the IC50 value of CEM/ara-G cells by that of CEM cells.