From: Gross cystic disease fluid protein 15 (GCDFP-15) expression in breast cancer subtypes
n | Events | % pCR | OR | 95% CI | p | |
---|---|---|---|---|---|---|
GCDFP-15 | 0.106 | |||||
Negative | 363 | 77 | 21.2 | 1 | - | |
Positive | 239 | 38 | 15.9 | 0.70 | 0.46-1.08 | |
HR | <0.0001 | |||||
Negative | 175 | 61 | 34.9 | 1 | - | |
Positive | 401 | 45 | 11.2 | 0.24 | 0.15-0.37 | |
HER2 | <0.0001 | |||||
Negative | 478 | 77 | 16.1 | 1 | - | |
Positive | 116 | 36 | 31.0 | 2.34 | 1.48-3.72 | |
Biological tumor types | <0.0001 | |||||
HR+/HER2- | 328 | 28 | 8.5 | 1 | - | |
HER2+ (HR+/-) | 111 | 34 | 30.6 | 4.73 | 2.70-8.28 | |
HR-/HER2- | 130 | 43 | 33.1 | 5.30 | 3.11-0.02 | |
Age | 0.001 | |||||
< 50 years | 273 | 68 | 24.9 | 1 | - | |
> = 50 years | 329 | 47 | 14.3 | 0.50 | 0.33-0.76 | |
Histological type | ||||||
Ductal/others | 554 | 113 | 20.4 | 1 | - | |
Lobular | 48 | 2 | 4.2 | 0.17 | 0.04-0.71 | |
Grading | <0.0001 | |||||
G1-2 | 463 | 74 | 16.0 | 1 | - | |
G3 | 138 | 41 | 29.7 | 2.22 | 1.43-3.46 | |
cT | 0.098 | |||||
cT1-2 | 395 | 83 | 21.0 | 1 | - | |
cT3-4 | 196 | 30 | 15.3 | 0.68 | 0.43-1.07 | |
cN | 0.809 | |||||
cN0 | 261 | 49 | 18.8 | 1 | - | |
cN+ | 322 | 63 | 19.6 | 1.05 | 0.70-1.59 |