From: Ectopic TSH-secreting pituitary tumor: a case report and review of prior cases
Case number | First | Second | Third | Fourth | Fifth |
---|---|---|---|---|---|
Reference | 2 | 3 | 4 | 5 | This report |
Gender | F | M | F | F | M |
Age of onset (y) | 45 | 34 | - | 34 | 40 |
Age of diagnosis | 66 | 52 | 50 | 49 | 41 |
Location of tumor | nasopharynx | ||||
Follow up | no recurrence at 2 months | recurrence at 10 months | no recurrence at 4 months | no recurrence at 3 months | no recurrence at 48 months |
IHC | TSH(+) | TSH(+) | TSH(+) | TSH(+) | TSH(+) |
GH(+) | GH(-) | GH(+) | GH(+) | GH(+) | |
PRL(+) | PRL(-) | PRL(-) | PRL(+) | PRL(-) | |
FSH(+) | FSH(-) | FSH(+) | FSH(-) | FSH(-) | |
ACTH(+) | ACTH(-) | ACTH(-) | ACTH(-) | ACTH(-) | |
LH(+) | LH(-) | LH(+) | LH(-) | LH(-) | |
Ultrastructure | N/A | N/A | N/A | consisted of monomorphous cells with secretory granules of small thyrotroph-like cells | consisted of polymorphous cells with secretory granules |
Octreotide inhibition test | N/A | N/A | N/A | yes | yes |
TRH stimulating test | N/A | N/A | N/A | N/A | yes |