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Table 1 Segmented regression analysis showing changes in intercept and changes in slope on FOBT participation rates following each initiative, 1994-2012

From: Evaluating the impact of public health initiatives on trends in fecal occult blood test participation in Ontario

Initiative (Segment) Intercept* Slope^
  Change in Intercept (Δ)  95% CI Change in slope (Δ) 95% CI
Baseline (April 94-October 96)    −2.4¥‡ (−3.9--0.9)
RCT (October 96-January 01) −3.2 (−13.1-7.9) 6.1 (4.3-7.9)
CTFPHC (January 01-July 05) 6.8 (−2.8-17.3) 0.3 (−0.6–1.3)
FI (July 05- April 08) −1.5 (−11.9–10.1) 2.2 (0.7– 3.8)
CCC launch (April 08-April 10) 35.4 (18.3–54.9) −9.7 (−12--7.4)
2-year anniversary (April 10 –March 12) 13.5 (−1.6–30.9) 7.2 (3.9–10.5)
  1. *Difference between pre and post initiative intercepts interpreted as step change and calculated as QPC = (exp βINTi -1 )* 100.
  2. ^Difference between pre and post initiative slopes taking into account the trend before the initiative and calculated as QPC = (exp βINT*TIMEi -1 )* 100.
  3. ¥Baseline slope.
  4. ‡Statistically significant if 95% confidence interval does not cross zero.
  5. RCT: Publication of the second and third randomized controlled trials in November 1996.
  6. CTFPHC: Publication of the Canadian Task Force on Preventive Health Care guidelines for CRC screening in February 2001.
  7. FI: Announcement of PCP financial incentives in July 2005.
  8. CCC launch: ColonCancer Check program (CCC) Program launch, April 2008.
  9. 2 - year anniversary: ColonCancerCheck Program 2-year anniversary, April 2010.