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Table 3 T3 tertiles and risk of specific prognostic factors in breast cancer

From: T3 levels in relation to prognostic factors in breast cancer: a population-based prospective cohort study

Tumour group Tertile* Cases HR HR** HR***
   (n) (95% CI) (95% CI) (95% CI)
All Tertile 1 38 1.0 1.0 1.0
n = 149 Tertile 2 54 1.25 (0.85-1.84) 1.33 (0.90-1.97) 1.38 (0.93-2.04)
  Tertile 3 57 1.34 (0.92-1.97) 1.50 (1.01-2.23) 1.61 (1.07-2.43)
Grade I Tertile 1 12 1.00 1.00 1.00
n = 42 Tertile 2 20 1.51 (0.74-3.09) 1.57 (0.76-3.26) 1.68 (0.81-3.49)
  Tertile 3 10 0.79 (0.34-1.82) 0.84 (0.35-2.01) 0.97 (0.40-2.37)
Grade II Tertile 1 14 1.00 1.00 1.00
n = 56 Tertile 2 14 0.91 (0.43-1.19) 0.95 (0.45-2.01) 0.98 (0.46-2.69)
  Tertile 3 28 1.89 (1.00-3.50) 2.04 (1.04-4.00) 2.13 (1.06-4.30)
Grade III Tertile 1 7 1.00 1.00 1.00
n = 38 Tertile 2 17 2.21 (0.92-5.32) 2.30 (0.94-5.61) 2.34 (0.96-5.74)
  Tertile 3 14 1.90 (0.77-4.71) 2.04 (0.80-5.23) 2.14 (0.82-5.59)
Size ≤20 mm Tertile 1 28 1.00 1.00 1.00
n = 93 Tertile 2 31 1.01 (0.60-1.68) 1.04 (0.62-1.75) 1.09 (0.65-1.84)
  Tertile 3 34 1.15 (0.70-1.89) 1.21 (0.72-2.05) 1.36 (0.79-2.33)
Size >20 mm Tertile 1 6 1.00 1.00 1.00
n = 45 Tertile 2 20 3.02 (1.21-7.53) 3.21 (1.28-8.07) 3.19 (1.26-8.06)
  Tertile 3 19 3.01 (1.20-7.53) 3.33 (1.30-8.58) 3.17 (1.20-8.36)
Node positive Tertile 1 5 1.00 1.00 1.00
n = 39 Tertile 2 16 2.90 (1.06-7.92) 3.22 (1.17-8.87) 3.36 (1.22-9.30)
  Tertile 3 18 3.40 (1.26-9.16) 4.08 (1.47-11.32) 4.53 (1.60-12.83)
Node negative Tertile 1 27 1.00 1.00 1.00
n = 91 Tertile 2 33 1.11 (0.67-1.85) 1.13 (0.67-1.89) 1.18 (0.70-1.99)
  Tertile 3 31 1.08 (0.65-1.82) 1.12 (0.65-1.92) 1.20 (0.69-2.10)
ER positive Tertile 1 28 1.00 1.00 1.00
n = 105 Tertile 2 41 1.32 (0.82-2.15) 1.37 (0.84-2.23) 1.42 (0.87-2.32)
  Tertile 3 36 1.22 (0.74-1.99) 1.28 (0.77-2.15) 1.39 (0.82-2.36)
ER negative Tertile 1 6 1.00 1.00 1.00
n = 36 Tertile 2 11 1.67 (0.62-4.52) 1.75 (0.64-4.77) 1.85 (0.68-5.09)
  Tertile 3 19 3.01 (1.20-7.53) 3.24 (1.25-8.40) 3.52 (1.32-9.41)
PGR positive Tertile 1 27 1.00 1.00 1.00
n = 97 Tertile 2 36 1.21 (0.73-1.99) 1.25 (0.75-2.08) 1.27 (0.77-2.13)
  Tertile 3 34 1.19 (0.72-1.97) 1.26 (0.74-2.14) 1.32 (0.77-2.27)
PGR negative Tertile 1 7 1.00 1.00 1.00
n = 44 Tertile 2 16 2.09 (0.86-5.07) 2.15 (0.87-5.29) 2.35 (0.96-5.80)
  Tertile 3 21 2.87 (1.22-6.75) 3.03 (1.25-7.34) 3.52 (1.42-8.75)
  1. *Cut-offs: tertile 1 (<1.70 ), tertile 2 (1.70-1.90 ), and tertile 3 (>1.9 ), **adjusted for age, ***adjusted for age and oral contraceptives.
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