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Table 1 Primary and secondary outcomes of the review

From: Prevention and treatment of acute radiation-induced skin reactions: a systematic review and meta-analysis of randomized controlled trials

Outcome classification Outcome description
Primary Prevention
  The development of a radiation-induced skin reaction (yes/no).
  Treatment
  Level of skin toxicity/reactions at one week and two weeks following the onset of the skin reaction.
  Level of symptom severity at one week and two weeks following the onset of the skin reaction (physical or psychological).
Secondary Prevention
  Time taken to develop an erythema or dry desquamation.
  Treatment
  Quality of life.
  Time taken to heal.
  Level of skin toxicity/reactions at the completion of treatment and at the last follow-up.
  Maximum level of skin toxicity/reactions reported.
  Level of symptom severity at any time following the onset of treatment (physical or psychological), at the completion of radiation treatment and at the last follow-up.*
  Maximum level of symptom severity (physical or psychological) reported.*
  Prevention and Treatment
  Cost of the interventions (both direct and indirect cost, both to the participant and the health system).
  Participant satisfaction.
  Ease of use.
  Adverse effects (including allergic reactions).
  1. *All symptoms reported by eligible trials were included.
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