Table 1 Primary and secondary outcomes of the review

Primary

Prevention

The development of a radiation-induced skin reaction (yes/no).

Treatment

Level of skin toxicity/reactions at one week and two weeks following the onset of the skin reaction.

Level of symptom severity at one week and two weeks following the onset of the skin reaction (physical or psychological).

Secondary

Prevention

Time taken to develop an erythema or dry desquamation.

Treatment

Quality of life.

Time taken to heal.

Level of skin toxicity/reactions at the completion of treatment and at the last follow-up.

Maximum level of skin toxicity/reactions reported.

Level of symptom severity at any time following the onset of treatment (physical or psychological), at the completion of radiation treatment and at the last follow-up.*

Maximum level of symptom severity (physical or psychological) reported.*

Prevention and Treatment

Cost of the interventions (both direct and indirect cost, both to the participant and the health system).

Participant satisfaction.

Ease of use.

Adverse effects (including allergic reactions).