Figure 3
From: MicroRNA profile in very young women with breast cancer
Relative expression of the validated miRNAs which have significantly different expression in BCVY tumour samples. A: miRNAs with increased expression in women ≤35 years old (BCVY). B: miRNAs with decreased expression in BCVY. Measures of the expression were quantified using the qRT-PCR technique and calculated using the ΔΔCt method. Boxes represent the sample distribution with the mean, vertical lines mark the 10th percentile, and outliers are represented as dots. P-values are calculated via One-Way ANOVA, and Tukey’s method was implemented as a correction for multiple comparisons. The top p-value represents differences between those ≤35 (BCVY) and >65; the bottom-left represents differences between those >65 and those 45–65 (middle group, between 45 and 65 years old); and bottom-right, the differences between those 45–65 and those ≤35 (BCVY).