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Table 3 Method correlations between THxID -BRAF test and HRM and Sanger sequencing

From: Comparative evaluation of the new FDA approved THxID™-BRAF test with high resolution melting and sanger sequencing

  

HRM

Sanger sequencing

  

M

WT

Total

M

WT

Total

THxID -BRAF test

M

43

0

43

45

0

45

 

WT

3

66

69

0

62

62

 

Total

46

66

112

45

62

107

Positive agreement

 

93.5 (95% CI 82.5 - 97.8)

100.0 (95% CI 92.1 - 100.0)

Negative agreement

 

100.0 (95% CI 94.5 - 100.0)

100.0 (95% CI 94.2 - 100.0)

Overall agreement

 

97.3 (95% CI 92.4 - 99.1)

100.0 (95% CI 96.5 - 100.0)

  1. M: Mutation; WT: Wild-type.