Serial enumeration of circulating tumor cells predicts treatment response and prognosis in metastatic breast cancer: a prospective study in 393 patients

Table 2 CTC _KIN and association with PFS, OS, and progression at 3-month radiological examination

	CTC_BL(baseline)	CTC_1C(after 1st cycle)	PFS (months)	OS (months)	Progression
			Median [95% CI]	Median [95% CI]	Numbers (percentage)
Favorable	Negative (CTC _BL -)	Negative (CTC _1C -)	8.7 [6.6–11.5]	30.6 [27.4–na]	20/75 (27%)
Favorable	Positive (CTC _BL +)	Negative (CTC _1C -)	8.0 [5.5–12.1]	16.7 [13.6–na]	11/32 (34%)
Unfavorable	Positive (CTC _BL +)	Positive (CTC _1C +)	4.3 [3.6–6.1]	7.7 [6.1–13.1]	21/41 (51%)
Unfavorable	Negative (CTC _BL -)	Positive (CTC _1C +)	3.7 [2.5–na]	14.0 [5.7–na]	3/6 (50%)

ISSN: 1471-2407