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Table 4 Multivariate analysis: cox proportional hazards model for OS and DFS

From: Prognostic impact of MGMT promoter methylation and MGMT and CD133 expression in colorectal adenocarcinoma

  OS DFS
Variables HR (CI) p value HR (CI) p value
Sex (male/female) 2.69 (0.77-9.34) 0.118 1.56 (0.80-3.05) 0.186
Differentiation grade (well-moderate/poor) 0.62 (0.20-1.93) 0.412 1.24 (0.48-3.17) 0.652
Tumor grade (I-II/III-VI) 0.50 (0.18-1.35) 0.175 0.38 (0.19-0.73) 0.004*
Radiotherapy (no/yes) 0.41 (0.13-1.27) 0.123 0.64 (0.29-1.41) 0.276
Chemotherapy (no/yes) 0.48 (0.16-1.49) 0.210 0.50 (0.25-0.99) 0.049*
MGMT expression intensity (low/high) 3.73 (1.35-10.33) 0.011* 1.55 (0.81-2.99) 0.182
Percentage CD133 expression (low/high) 0.54 (0.18-1.65) 0.280 0.44 (0.22-0.86) 0.018*
  1. HR, Hazard ratio. CI, confidence interval. Statistically significant variables (*p < 0.05).