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Table 5 Multivariate Analysis of Risk Factors Associated with PEM-induced ILD

From: Pemetrexed for advanced non-small cell lung cancer patients with interstitial lung disease

  Odds ratio 95% CI P
Variable    
Age (<71 vs 71) 0.20 0.003-2.52 0.23
Gender (Female vs Male) 1.32 0.03-53.99 0.86
Smoking history (no vs yes) 4.68 0.09-443.12 0.44
Performance status (0–1 vs 2–3) 0.17 0.005-5.38 0.28
Number of line (1–2 vs 3-) 0.23 0.009-2.83 0.27
IIPs (no vs yes) 34.37 1.64-4566.21 0.019*
  1. *Statistically significant by Logistic regression analysis.