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Table 5 Criteria used to build a prognostic score for patient selection for RFA treatment of liver-only CLM in the context of effective modern-agent systemic therapies

From: Selection criteria for radiofrequency ablation for colorectal liver metastases in the era of effective systemic therapy: a clinical score based proposal

Variable

Reference category

Points

Systemic therapy

Objective response1

1

Number of CLM

≤ 3 CLM

1

Maximum size of CLM

≤ 3 cm2

1

CEA level

≤ 100 ng/mL

1

  1. Abbreviations: CEA, carcinoembryonic antigen; CLM, colorectal liver metastases; RFA, radiofrequency ablation.
  2. 1RECIST-defined response to the immediate preceding systemic therapy regimen before RFA treatment. 2after decrease of ≥30% in size following the immediate preceding systemic therapy regimen before RFA treatment.