Table 1 Rash rating scales used in this investigation
Grade | EGFR-Inhibitor induced rash scale | CTCAE Assessment scale |
|---|---|---|
0 | No rash | No rash |
1 | Isolated pustule or erythematous patch < 1 cm in diameter, on either face/head/neck or chest/back | Macular or papular eruption or erythema without associated symptoms |
2 | More than one erythematous patch or erythema and telangiectasia on either face/head/neck or chest/back | Macular or papular eruption or erythema with pruritus or other associated symptoms; localized desquamation or other lesions covering < 50% of body surface area |
3 | More than one pustule or papules on either face/head/neck or chest/back with no associated erythema or telangiectasia | Severe, generalized erythroderma or macular, papular or vesicular eruption; desquamation covering ≥ 50% body surface area |
4 | Both erythema/telangiectasia and pustules/papules limited to either face/head/neck or chest/back | Generalized exfoliative, ulcerative, or bullous dermatitis |
5 | Pustules or papules and erythema/telangiectasia present on both the face/head/neck region and the chest/back | Death |