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Table 3 Relation of stromal expression and clinicopathological features

From: Myofibroblastic stromal reaction and lymph node status in invasive breast carcinoma: possible role of the TGF-β1/TGF-βR1 pathway

 

Strong expression SMA*

Weak expression SMA**

 

Age

   

 ≤ 40

7

1

p = 0.9

 >40- ≤ 60

52

14

 

 > 60

58

16

 

Grade

   

 Grade 1

27

6

p = 0.98

 Grade 2

62

18

 

 Grade 3

33

9

 

Tumor shape

   

 Spiculated

86

20

p = 0.2

 Nodular

18

9

 

 Mixed

18

4

 

Tumor size

   

 ≤ 1 cm

28

12

p = 0.1

 > 1 - ≤ 2 cm

42

9

 

 > 2 cm

46

9

 

KI-67 index

   

 ≤ 15%

53

14

p = 0.9

 > 15%

59

18

 

Lymph node status

   

 Metastasis

52

8

p < 0.05

 No metastasis

40

16

 
  1. Significant P value is <0.05.
  2. *Strong expression means that > 50% of stromal cells express SMA (score +++ and ++++).
  3. **Weak expression means that < 50% of stromal cells express SMA (score + and ++).
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BMC Cancer

ISSN: 1471-2407

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