Immunohistochemical staining of HLTF in benign and malignant thyroid tumors and statistical analysis of HLTF staining in benign and malignant thyroid lesions. (A-B) A: follicular adenoma and B: papillary carcinoma. The scale bar is 50µm. (C) N: normal tissues, Ad: adenomas, HT: Hashimoto’s Thyroiditis, GD: Graves’ Diseases, CN: colloid nodules, PC: papillary carcinomas and FVPC: follicular variant of papillary carcinomas. The immunohistochemical expression was semi-quantitatively assessed in the nuclear compartment using the MI (MI nuc). The threshold of significance associated with the global multigroup comparison (Kruskal-Wallis test) is located in the higher right corner. Horizontal arrows represent the post-hoc comparison for the pairs of groups, with corresponding p-values.