TY - JOUR AU - Arcolia, Vanessa AU - Paci, Paula AU - Dhont, Ludovic AU - Chantrain, Gilbert AU - Sirtaine, Nicolas AU - Decaestecker, Christine AU - Remmelink, Myriam AU - Belayew, Alexandra AU - Saussez, Sven PY - 2014 DA - 2014/07/08 TI - Helicase-like transcription factor: a new marker of well-differentiated thyroid cancers JO - BMC Cancer SP - 492 VL - 14 IS - 1 AB - The preoperative characterization of thyroid nodules is a challenge for the clinicians. Fine-needle aspiration (FNA) is the commonly used pre-operative technique for diagnosis of malignant thyroid tumor. However, many benign lesions, with indeterminate diagnosis following FNA, are referred to surgery. There is an urgent need to identify biomarkers that could be used with the FNA to distinguish benign thyroid nodules from malignant tumors. The purpose of the study is to examine the level of expression of the helicase-like transcription factor (HLTF) in relation to neoplastic progression of thyroid carcinomas. SN - 1471-2407 UR - https://doi.org/10.1186/1471-2407-14-492 DO - 10.1186/1471-2407-14-492 ID - Arcolia2014 ER -