Skip to main content

Table 3 Diagnostic values in early stage ESCC combining assay seromarkers

From: Establishment of using serum YKL-40 and SCCA in combination for the diagnosis of patients with esophageal squamous cell carcinoma

Combinations

Sensitivity(%)

Specificity(%)

PPV(%)

NPV(%)

YKL-40

70.21

84.13

62.26

88.33

CEA

10.64

96.80

55.56

74.23

CYFRA21-1

40.43

92.06

65.52

80.56

YKL-40 or CEA

70.21

83.20

61.11

88.14

YKL-40 or CYFRA21-1

78.72

77.78

56.92

90.74

CEA or CYFRA21-1

46.80

89.60

62.86

81.75

YKL-40 or CEA or CYFRA21-1

78.72

76.80

56.06

90.57

  1. Cut-off values: 58.0 ng/ml for YKL-40; 5.0 ng/ml for CEA; 3.3 ng/ml for CYFRA21-1; 1.5 ng/ml for SCCA.
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us