Figure 5
From: IL-1β mediates MCP-1 induction by Wnt5a in gastric cancer cells
Promotion of macrophage chemotaxis by Wnt5a-conditioned medium. Wnt5a-conditioned medium from Wnt5a-transfected BGC-803 cells enhanced macrophage migration by transwell analysis, which was inhibited by the addition of MCP-1 neutralizing antibody AF-479-NA (0.1 μg/ml) into the medium or the pretreatment of Wnt5a-transfected BGC-803 cells with rIL-1Ra. *P < 0.01 vs Control; **P < 0.01 vs Wnt5a V. Control V: control vector; Wnt5a V: Wnt5a vector; rIL-1Ra: recombinant IL-1 receptor antagonist. Data are expressed as mean ± SD, n = 3.