Figure 4
From: IL-1β mediates MCP-1 induction by Wnt5a in gastric cancer cells
Mediation of IL-1β in Wnt5a-induced MCP-1 upregulation in gastric cancer cells. (A) and (B) rIL-1Ra (0.5 μg/ml) inhibited MCP-1 upregulation by Wnt5a transfection in BGC-803 cells and HGC-27 cells. (C) and (D) rIL-1β (1 μg/ml) stimulated MCP-1 expression in BGC-803 cells and HGC-27 cells. *P < 0.01 vs Wnt5a V; **P < 0.01 vs Control. Control V: control vector; Wnt5a V: Wnt5a vector; rIL-1Ra: recombinant IL-1 receptor antagonist; rIL-1beta: recombinant IL-1β. Data are expressed as mean ± SD, n = 3.