Figure 2
From: IL-1β mediates MCP-1 induction by Wnt5a in gastric cancer cells
Stimulation of MCP-1 expression by Wnt5a in gastric cancer cells. (A) and (B) Wnt5a transfection induced MCP-1 expression in BGC-803 cells and HGC-27 cells by real-time PCR and ELISA. (C) and (D) Recombinant Wnt5a (0.5 μg/ml) treatment promoted MCP-1 expression in BGC-803 cells and HGC-27 cells. (E) Wnt5a siRNA suppressed MCP-1 expression in MKN-45 cells. *P < 0.01 vs Control. Control V: control vector; Wnt5a V: Wnt5a vector; rWnt5a: recombinant Wnt5a. Control si: control siRNA; Wnt5a si: Wnt5a siRNA. Data are expressed as mean ± SD, n = 3.