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Figure 2 | BMC Cancer

Figure 2

From: Family-specific, novel, deleterious germline variants provide a rich resource to identify genetic predispositions for BRCAx familial breast cancer

Figure 2

Comparison of the variants in BRCAx families and probands. A. Comparison in the three families. B. Comparison in the probands. The results show that the variants detected in the cancer-affected family members are highly family-specific. The higher rate (18%) of the shared variants in the probands are likely due to the remaining normal variants not filtered in the probands and the larger number of families represented by the probands than the three families.

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