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Table 1 Characteristics of included studies

From: Association between the TP53 codon 72 polymorphism and risk of oral squamous cell carcinoma in Asians: a meta-analysis

Reference Country OSCC Diagnostic method Source of control Control Genotype method HWE
HPV Total ProPro ArgPro ArgArg Total ProPro ArgPro ArgArg
Tandle 2001 [19] India No 72 14 52 6 Histopathological PB 153 31 100 22 PCR <0.001
Nagpal 2002 [20] India Yes 110 21 58 31 Histological PB 26 2 11 13 PCR 0.876
Kietthubthew 2003 [21] Thailand No 97 21 44 32 Histological PB 97 28 34 35 PCR 0.004
Hsieh 2005 [22] China No 629 114 328 187 Histological PB 371 66 177 128 PCR-RFLP 0.723
Kuroda 2007 [24] Japan No 100 15 44 41 Histological HB 271 45 117 109 PCR-RFLP 0.159
Bau 2007 [23] China No 137 21 70 46 NA HB 105 22 65 18 PCR 0.139
Lin 2008 [25] China No 297 46 155 96 Histological PB 280 52 156 72 PCR-RFLP 0.085
Tu 2008 [26] China No 189 30 106 53 NA HB 116 15 60 41 PCR 0.337
Misra 2009 [27] India No 308 66 155 87 Histopathological HB 342 98 159 85 PCR 0.203
Saini 2011 [28] Malaysia Yes 99 37 40 22 NA HB 90 23 39 28 PCR 0.215
Saleem 2013 [29] Pakistan No 260 125 113 22 NA PB 260 33 23 204 PCR-SSCP <0.001
  1. OSCC, oral squamonus cell carcinoma; HPV, human papillomavirus; NA, not available; HB, hospital-based; PB, population-based; HWE, Hardy Weinberg Equilibrium.