Association between the TP53 codon 72 polymorphism and risk of oral squamous cell carcinoma in Asians: a meta-analysis

Table 1 Characteristics of included studies

Reference	Country	OSCC					Diagnostic method	Source of control	Control				Genotype method	HWE
Reference	Country	HPV	Total	ProPro	ArgPro	ArgArg	Diagnostic method	Source of control	Total	ProPro	ArgPro	ArgArg	Genotype method	HWE
Tandle 2001 [19]	India	No	72	14	52	6	Histopathological	PB	153	31	100	22	PCR	<0.001
Nagpal 2002 [20]	India	Yes	110	21	58	31	Histological	PB	26	2	11	13	PCR	0.876
Kietthubthew 2003 [21]	Thailand	No	97	21	44	32	Histological	PB	97	28	34	35	PCR	0.004
Hsieh 2005 [22]	China	No	629	114	328	187	Histological	PB	371	66	177	128	PCR-RFLP	0.723
Kuroda 2007 [24]	Japan	No	100	15	44	41	Histological	HB	271	45	117	109	PCR-RFLP	0.159
Bau 2007 [23]	China	No	137	21	70	46	NA	HB	105	22	65	18	PCR	0.139
Lin 2008 [25]	China	No	297	46	155	96	Histological	PB	280	52	156	72	PCR-RFLP	0.085
Tu 2008 [26]	China	No	189	30	106	53	NA	HB	116	15	60	41	PCR	0.337
Misra 2009 [27]	India	No	308	66	155	87	Histopathological	HB	342	98	159	85	PCR	0.203
Saini 2011 [28]	Malaysia	Yes	99	37	40	22	NA	HB	90	23	39	28	PCR	0.215
Saleem 2013 [29]	Pakistan	No	260	125	113	22	NA	PB	260	33	23	204	PCR-SSCP	<0.001

OSCC, oral squamonus cell carcinoma; HPV, human papillomavirus; NA, not available; HB, hospital-based; PB, population-based; HWE, Hardy Weinberg Equilibrium.

ISSN: 1471-2407