Table 1 Clinicopathological and molecular data of colon adenomas and carcinomas

Age

65.4 ± 4.4

60.6 ± 9.8

62.2 ± 8.2

70.8 ± 11.3

0.019 ^(a)

Gender (M/F)

4/4

13/6

6/6

6/7

0.57

Duke’s stage

NA

NA

7/5

11/2

0.20

(A or B/C)

Grade ¹

NA

NA

12/0

9/4

0.096

(W-M/P)

KRAS Mutations

4/8

0/19

4/12

0/13

0.0011

(mut/total)

BRAF Mutations

0/8

19/19

4/12

9/13

2.2×10 ^-6

(mut/total)

hMLH1 Methylation (+/total )

0/8

0/19

0/12

5/13

8.6×10 ^-4

Hypermethylation ²

1.8 ± 1.4%

1.2 ± 0.6%

1.2 ± 0.6%

1.9 ± 1.2%

0.15^(a)

Hypomethylation ²

0.6 ± 0.4%

0.3 ± 0.2%

1.0 ± 0.5%

1.0 ± 0.6%

5.8×10 ^{-4 (a)}