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Table 1 The clinical and pathological features in 46 human conventional osteosarcomas

From: The genetic basis for inactivation of Wnt pathway in human osteosarcoma

  N Disease free survival Overall survival
P HR 95.0% CI P HR 95.0% CI
L U L U
Sex Male 29 0.86     0.07*    
Female 29 0.86 1.11 0.36 3.44 0.08 3.49 0.86 14.28
Age group <=15 y 14 0.76     0.79    
15-20 y 23 0.94 1.10E + 04 0 1.40E + 116 0.5 1.82 0.32 10.42
21-30 y 11 0.94 3.70E + 04 0 4.40E + 116 0.72 0.73 0.13 4.05
31-40 y 1 0.93 5.30E + 04 0 6.40E + 116 0.97 0 0 1.90E + 282
>40 y 9 1 1.02 0 3.90E + 225 0.99 0 0  
Tumor location limbs 51 0.28     0.97    
Others 7 0.48 23.34 0.004 1.60E + 05 0.97 0.97 0.12 7.72
Enneking stage I 4 0.96     0.43    
IIA 19 0.78 0.71 0.06 7.88 0.17 0.1 0.004 2.74
IIB 2 0.631 0.59 0.07 5.01 0.1 0.09 0.01 1.61
III 1 0.897 0.83 0.05 13.39 0.99 0 0  
Neoadjuvant chemotherapy No 10 0.51     1.5E-4*    
Yes 30 0.51 1.51 0.44 5.15 0.003 11.85 2.36 59.45
Adjuvant chemotherapy No 3 0.21     0.41    
Yes 19 0.43 0.04 0 129.34 0.61 0.04 0 1.20E + 04
Recurrence No 50      0.49    
Yes 8      0.49 2.05 0.26 16.26
Metastasis No 38      0.045*    
Yes 11      0.436 0.01 0 2.40E + 03
  1. *Significantly different; L: lower; U: upper.