BMC Cancer

Table 3 Association of serum PFOS and PFOA levels to CRC diagnosis by gender in adults ≥ 21 years of age*

From: Inverse association of colorectal cancer prevalence to serum levels of perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in a large Appalachian population

	Men only (N=114 cases)						Women only (N=94 cases)						P for interaction
	Cases	Controls	Odds ratio	95% CI		P	Cases	Controls	Odds ratio	95% CI		P
				Lower	Upper					Lower	Upper
*PFOS quartiles*
First (reference)	54	5645	1.00				32	6002	1.00				0.30
Second	18	5743	0.34	0.20	0.59	0.00001	19	6122	0.38	0.21	0.67	0.001
Third	20	5708	0.28	0.17	0.47	<0.00001	19	6065	0.32	0.18	0.57	0.0001
Fourth	22	5763	0.20	0.12	0.34	<0.00001	24	6103	0.31	0.18	0.53	0.00002
Test for trend						<0.00001						<0.00001
*PFOA quartiles*
First (reference)	39	5665	1.00				22	5997	1.00				0.04
Second	18	5761	0.35	0.19	0.64	0.001	23	6130	0.70	0.38	1.26	0.23
Third	27	5719	0.49	0.29	0.81	0.006	21	6096	0.56	0.31	1.02	0.06
Fourth	30	5714	0.53	0.32	0.86	0.01	28	6069	0.76	0.44	1.32	0.33
Test for trend						0.002						0.32

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ISSN: 1471-2407

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