Table 2 Main results of meta-analysis according to the different cutoff values of ALDH1A1expression

Tumor size

1.30

0.92-1.83

1.29*

1.01-1.65

1.24

0.95-1.61

1.37*

1.01-1.86

1.31*

1.06-1.62

1.19

0.66-2.14

LNM

1.43

0.99-2.07

1.20

0.94-1.54

1.33*

1.03-1.72

1.16

0.82-1.64

1.27*

1.03-1.56

1.29

0.33-4.97

SBR grade

2.33*

1.22-4.43

2.32*

1.20-4.49

2.16*

1.31-3.55

2.41*

1.16-5.04

2.37*

1.57-3.58

2.94

0.80-10.77

ER

0.46*

0.34-0.61

0.43*

0.33-0.55

0.47*

0.36-0.61

0.42*

0.32-0.54

0.41*

0.33-0.50

0.54*

0.36-0.82

PR

0.54*

0.30-0.98

0.46*

0.25-0.84

0.56*

0.33-0.96

0.45*

0.24-.0.84

0.43*

0.29-0.64

0.82

0.42-1.61

HER2

1.39

0.78-2.48

3.19*

1.67-6.08

2.39*

1.33-4.28

1.78

0.93-3.42

2.66*

1.76-4.03

0.89

0.54-1.48

OS/SS/RS

2.65*

1.82-3.86

2.33*

1.60-3.38

2.39*

1.83-3.13

3.10*

2.02-4.75

2.25*

1.71-2.95

3.51*

2.33-5.31

DFS/MFS/RFS

2.65*

1.54-4.57

2.04*

1.53-2.73

1.95*

1.33-2.85

2.36*

1.67-3.32

1.93*

1.41-2.65

2.68*

1.73-4.13

Parameter

Antibodies used in studies

Surgery situation of patients

Overall

BD

Abcam

Surgery

NS/Partly

OR/HR

95% CI

OR/HR

95% CI

OR/HR

95% CI

OR/HR

95% CI

OR/HR

95% CI

P

I ²

Tumor size

1.30*

1.06-1.60

1.05

0.38-2.93

-

-

-

-

1.29*

1.06-1.58

0.012

0.0%

LNM

1.34*

1.08-1.67

0.76

0.39-1.48

-

-

-

-

1.27*

1.03-1.56

0.024

0.0%

SBR grade

2.65*

1.73-4.08

1.27

0.63-2.56

-

-

-

-

2.39*

1.61-3.54

0.000

70.4%

ER

0.43*

0.35-0.52

0.43*

0.36-0.52

-

-

-

-

0.43*

0.36-0.52

0.000

42.3%

PR

0.54*

0.36-0.80

0.30*

0.15-0.57

-

-

-

-

0.50*

0.35-0.71

0.000

65.1%

HER2

1.85*

1.19-2.87

2.83

0.53-15.07

-

-

-

-

1.95*

1.29-2.95

0.002

65.5%

OS/SS/RS

-

-

-

-

2.87*

2.17-3.80

1.76*

1.06-2.91-

2.58*

2.05-3.23

0.000

38.0%

DFS/MFS/RFS

2.07*

1.60-2.69

4.60*

1.53-13.81

2.09*

1.60-2.75

2.72*

1.32-5.60

2.16*

1.68-2.79

0.000

0.0%