Figure 8From: MicroRNA-26a regulates glucose metabolism by direct targeting PDHX in colorectal cancer cells The molecular mechanism of miR-26a involved in glucose metabolism in CRC cells. MiR-26a directly targets the PDHX to suppress the conversion of pyruvate to acetyl-CoA, thus blocking the key step of glycolysis to the citric acid cycle. “┤” represents the inhibition effect.Back to article page