Figure 7
From: MicroRNA-26a regulates glucose metabolism by direct targeting PDHX in colorectal cancer cells
The miR-26a regulates glucose metabolism in SW620 cells. (A) The suppressed expression of miR-26a with its inhibitor treatment greatly induced the decrease of glucose uptake. A non-targeting oligonucleotide was used as the control. The miR-26a inhibits the conversion of pyruvate to acetyl-CoA in SW620 cells. (B, C) The suppressed expression of miR-26a with its inhibitor treatment induced the decrease of pyruvate content and the up-regulation of the acetly-CoA production. A non-targeting oligonucleotide was used as the control. The average values ± the standard error of the mean (SEM) of three separate experiments were plotted. *p <0.05, **p < 0.005.