Figure 2From: Monitoring changes in circulating tumour cells as a prognostic indicator of overall survival and treatment response in patients with metastatic melanoma Prognostic significance of CTC number. Kaplan-Meier curves for (A, D) OS, (B, E) PFS and (C, F) time to response of all melanoma patients with a positive and negative change in CTC number after treatment, calculated as the slope of plotted CTC counts over the first 12Â weeks. Patients treated with the B-Raf inhibitor vemurafenib were analysed separately (D, E and F).Back to article page