Table 3 Univariate analysis of clinical and histological parameters on overall survival
From: Inaugural bone metastases in non-small cell lung cancer: a specific prognostic entity?
Tumoral and patients characteristics | N | OS (months) | HR | p |
|---|---|---|---|---|
OMS 0-1 | 32 | 12 | 2.10 | 0.007 |
Vs 2-3 | 21 | 6.2 | CI 95% 1.11-3.9 | |
Weight loss ≥ 10% | 12 | 3.4 | 2.58 | 0.002 |
< 10% | 41 | 11 | CI 95% 1.06-6 | |
Adenocarcinoma | 43 | 8.3 | 0.93 | 0.84 - NS |
Vs others histological subtypes | 12 | 7.8 | CI 95% 0.49- 1.8 | |
TTF1 negative | 22 | 6.4 | 0.54 | 0.03 |
Vs positive | 28 | 15.4 | CI 95% 0.29- 1 | |
T0-1 | 26 | 15.5 | 2.37 | 0.0013 |
vs T2-3-4 | 23 | 6.6 | CI 95% 1.25-4.4 | |
No visceral involvement | 25 | 12.6 | 1.8 | 0.025 |
Vs visceral involvement | 30 | 6.4 | CI 95% 1–3.13 | |
Solitary bone metastasis | 10 | 14.2 | 0.42 | 0.0059 |
Vs multiple bone and/or visceral metastasis | 45 | 7.6 | CI 95% 0.23-0.73 | |
Revealing site: spine | 19 | 6,3 | 1.72 | 0.054 |
vs other sites | 36 | 10 | CI 95% 0.90-3.27 | |
Spinal epidural metastasis | ||||
Yes | 9 | 3 | 2.4 | 0.017 |
No | 46 | 9,7 | CI 95% 0.83-5.95 |