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Table 3 Univariate analysis of clinical and histological parameters on overall survival

From: Inaugural bone metastases in non-small cell lung cancer: a specific prognostic entity?

Tumoral and patients characteristics N OS (months) HR p
OMS 0-1 32 12 2.10 0.007
Vs 2-3 21 6.2 CI 95% 1.11-3.9  
Weight loss ≥ 10% 12 3.4 2.58 0.002
< 10% 41 11 CI 95% 1.06-6  
Adenocarcinoma 43 8.3 0.93 0.84 - NS
Vs others histological subtypes 12 7.8 CI 95% 0.49- 1.8  
TTF1 negative 22 6.4 0.54 0.03
Vs positive 28 15.4 CI 95% 0.29- 1  
T0-1 26 15.5 2.37 0.0013
vs T2-3-4 23 6.6 CI 95% 1.25-4.4  
No visceral involvement 25 12.6 1.8 0.025
Vs visceral involvement 30 6.4 CI 95% 1–3.13  
Solitary bone metastasis 10 14.2 0.42 0.0059
Vs multiple bone and/or visceral metastasis 45 7.6 CI 95% 0.23-0.73  
Revealing site: spine 19 6,3 1.72 0.054
vs other sites 36 10 CI 95% 0.90-3.27  
Spinal epidural metastasis     
Yes 9 3 2.4 0.017
No 46 9,7 CI 95% 0.83-5.95