Figure 3From: NQO1 overexpression is associated with poor prognosis in squamous cell carcinoma of the uterine cervix NQO1 protein expression in cervical lesions using IHC. (A) NQO1 protein was negative in normal cervical epithelia. (B) NQO1 protein staining was positive in dysplastic cells of CIN-3, but negative in adjacent normal cervical glands (arrows). (C) NQO1 protein showed diffuse and strong cytoplasmic-positive staining in late-stage cervical SCC. (D) NQO1 was weakly positive in early-stage cervical SCC. (E) NQO1 protein was negative in cervical SCC without metastasis. (F) This case of SCC showed a rare nuclear staining pattern.Back to article page