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Table 1 Main characteristics of all studies included in the meta-analysis

From: Association of interferon regulatory factor 4 gene polymorphisms rs12203592 and rs872071 with skin cancer and haematological malignancies susceptibility: a meta-analysis of 19 case–control studies

rs12203592 Case    Control    
First author Year Country  Ethnicity Cancer type Source of controls CC TC TT CC TC TT HWE
Gathany [24] 2009 USA Mixed NHL PB 730 239 19 605 202 18 0.814
Wang 1 [40] 2009 USA Mixed NHL PB 299 123 13 357 143 15 0.882
Wang 2 [40] 2009 USA Mixed NHL PB 332 157 29 283 160 19 0.541
Kvaskoff [34] 2011 France Caucasians Melanoma HB 654 307 48 871 518 79 0.862
Han 1 [35] 2011 USA Caucasians Melanoma HB 123 54 11 450 163 19 0.369
Han 2 [35] 2011 USA Caucasians Melanoma HB 126 68 20 565 232 29 0.394
Pena-Chilet [32] 2013 Spain Caucasians Melanoma PB 398 121 19 242 101 19 0.055
Han 3 [35] 2011 USA Caucasians SCC HB 156 80 15 450 163 19 0.369
Han 4 [35] 2011 USA Caucasians SCC HB 143 110 20 565 232 29 0.394
Han 5 [35] 2011 USA Caucasians BCC HB 139 54 20 503 191 24 0.269
Han 6 [35] 2011 USA Caucasians BCC HB 174 81 19 565 232 29 0.394
rs872071 Case Control
First author Year Country  Ethnicity Cancer type Source of controls AA AG GG AA AG GG HWE
Di Bernardo 1 [27] 2008 UK Caucasians CLL HB 63 248 190 305 720 411 0.754
Di Bernardo 2 [27] 2008 UK Caucasians CLL PB 67 232 201 183 391 202 0.816
Lan [36] 2010 USA Asians CLL HB 21 36 12 602 534 127 0.978
Crowther-Swanepoel [37] 2010 UK Caucasians CLL PB 74 203 117 129 179 89 0.076
Broderick 1 [39] 2010 UK Caucasians HL PB 16 55 36 228 519 278 0.629
Broderick 2 [39] 2010 UK Caucasians HL PB 83 198 118 259 562 269 0.302
Pratt [38] 2010 UK Caucasians MM PB 82 169 101 183 388 200 0.846
Qiao [33] 2013 China Asians NHL HB 341 381 64 777 653 112 0.112
  1. BCC: Basal cell carcinoma; SCC: Squamous cell carcinoma; HL: Hodgkin lymphoma; NHL: Non-Hodgkin lymphoma; MM: Multiple myeloma; CLL: Chronic lymphocytic leukaemia.
  2. PB: population based; HB: hospital based.
  3. HWE: Hardy-Weinberg equilibrium.