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Table 4 Univariate Cox regression analysis of the parameters of metabolic response predictive of overall survival

From: Volumetric FDG-PET predicts overall and progression- free survival after 14 days of targeted therapy in metastatic renal cell carcinoma

 

After 14 days

After 28 days

 

Above versus below the median value*

Metabolic response versus no response

Above versus below the median value*

Metabolic response versus no response

SULpeaka

2.77(1.10-6.98)

0.38(0.15-0.93)*

4.07(1.54-10.78)*

0.94(0.41-2.20)

SUVmax

1.31(0.62-2.74)

0.58(0.26-1.28)

2.06(0.93-4.54)

0.50(0.21-1.19)

TLG2.5

5.35(2.08-13.75)*

0.22(0.09-0.53)*

3.54(1.52-8.27)*

0.40(0.18-0.92)*

TLG50

4.07(1.77-9.38)*

0.25(0.11-0.57)*

4.41(1.79-10.87)*

0.30(0.12-0.74)*

HottestSULpeaka

1.61(0.71-3.66)

0.38(0.15-0.93)*

3.20(1.25-8.18)*

0.84(0.37-1.91)

HottestSUVmax

1.32(0.60-2.93)

0.60(0.25-1.44)

1.92(0.88-4.18)

0.97 (0.41-2.31)

HottestTLG2.5

6.15(2.32-16.32)*

0.29(0.12-0.66)*

5.43(2.17-13.58)*

0.18(0.07-0.44)*

HottestTLG50

2.30(1.06-4.99)*

0.20(0.09-0.47)*

2.65(1.15-6.08)*

0.35(0.15-0.79)*

  1. aAccording to PERCIST1.0, * = Significant within a confidence interval of 95%.