Table 1 Subject eligibility criteria in the PROLUCA trial

All subjects are assigned for curative lung cancer surgery at Department of Cardiothoracic Surgery RT at Copenhagen University Hospital (Rigshospitalet).

Screened for eligibility criteria at Bispebjerg University Hospital and Gentofte Hospital.

At least 18 years old.

Performance status 0–2 (WHO) [46].

Capable of participating in the described tests and intervention.

Living in the City of Copenhagen or surrounding Municipalities.

Reside within driving distance of Copenhagen Centre for Cancer and Health and capable of managing transportation as necessitated by the clinic-based assessments and supervised exercise interventions.

Ability to read and understand Danish.

Approval by primary surgeon.

To examine for any contraindication in participating in physical exercise.

Exclusion criteria

Presence of metastatic disease or surgical inoperability.

Diagnosis of Lung Cancer not verified by histological diagnosis.

Cardiac disease [6, 47].

Decompensated heart failure, severe aortic stenosis, uncontrolled arrhythmia, acute coronary syndrome.

Contraindications to maximal exercise testing as recommended by the American Thoracic Society and exercise testing guidelines for cancer patients [48].