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Table 1 Genes up-regulated by hypoxia

From: Hypoxia increases membrane metallo-endopeptidase expression in a novel lung cancer ex vivo model – role of tumor stroma cells

Gene symbol

Gene name

P

Fold-change

PPP1R3C

Protein phosphatase 1, regulatory (inhibitor) subunit 3C

7,6E-07

2,5

HK2

Hexokinase 2

3,4E-06

2,1

GBE1

Glucan (1,4-alpha-), branching enzyme 1

3,9E-06

2,3

KDM3A

Lysine (K)-specific demethylase 3A

5,6E-06

2,0

KCTD11

Potassium channel tetramerisation domain containing 11

6,3E-06

2,2

FAM115C

Family with sequence similarity 115, member C

1,1E-05

2,3

BNIP3

BCL2/adenovirus E1B 19 kDa interacting protein 3

3,6E-05

2,1

DNAJB9

DnaJ (Hsp40) homolog, subfamily B, member 9

4,6E-05

2,4

MME

Membrane metallo-endopeptidase

7,3E-05

2,5

IL8

Interleukin 8

8,3E-05

2,3

DTNA

Dystrobrevin, alpha

9,0E-05

2,1

C7orf68

Chromosome 7 open reading frame 68

9,5E-05

2,4

LOX

Lysyl oxidase

1,2E-04

2,7

HSPA13

Heat shock protein 70 kDa family, member 13

1,7E-04

2,2

LRRC49

Leucine rich repeat containing 49

1,9E-04

2,0

STC2

Stanniocalcin 2

2,2E-04

2,2

TREM1

Triggering receptor expressed on myeloid cells 1

2,5E-04

2,3

CDR1

Cerebellar degeneration-related protein 1

2,5E-04

2,2

ADM

Adrenomedullin

2,5E-04

2,2

NUCB2

Nucleobindin 2

3,6E-04

2,4

TSPYL2

TSPY-like 2

5,8E-04

2,0

DDIT3

DNA-damage-inducible transcript 3

6,3E-04

2,5

C1orf129

Chromosome 1 open reading frame 129

8,2E-04

3,4

FICD

FIC domain containing

1,0E-03

2,4

FABP3

Fatty acid binding protein 3

1,3E-03

2,0

ABI3BP

ABI family, member 3 (NESH) binding protein

1,3E-03

2,0

NOG

Noggin

1,4E-03

2,1

SEC11C

SEC11 homolog C

4,0E-03

2,2