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Table 4 Multivariate Cox regression analysis on overall and disease-specific survival of primary melanoma patients

From: A combination of p300 and Braf expression in the diagnosis and prognosis of melanoma

 

Overall survival

Disease-specific survival

Variables

߆

SE

HR (95% CI)

p-value

ß

SE

HR (95% CI)

p-value

 AJCC

1.302

0.170

3.68 (2.63-5.13)

1.98 × 10-14

1.457

0.182

4.29 (3.01-6.13)

1.13 × 10-14

 Braf

0.178

0.190

1.20 (0.82-1.73)

0.348

0.110

0.196

1.12 (0.76-1.64)

0.575

 Nuclear p300

-0.508

0.161

0.60 (0.44-0.83)

0.002

-0.525

0.169

0.59 (0.42-0.82)

0.002

 Cytoplasmic p300

0.049

0.163

1.05 (0.76-1.45)

0.764

0.091

0.171

1.10 (0.78-1.53)

0.595

  1. Coding of variables: AJCC was coded as 1 (stages I & II) and 2 (stages (III & IV). Braf and p300 expression was coded as 1 (low staining) and 2 (high staining).
  2. †β: regression coefficient.
  3. Abbreviations: SE standard error of β, HR hazard ratio, CI confidence interval.
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BMC Cancer

ISSN: 1471-2407

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