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Table 4 Multivariate Cox regression analysis on overall and disease-specific survival of primary melanoma patients

From: A combination of p300 and Braf expression in the diagnosis and prognosis of melanoma

  Overall survival Disease-specific survival
Variables ß SE HR (95% CI) p-value ß SE HR (95% CI) p-value
 AJCC 1.302 0.170 3.68 (2.63-5.13) 1.98 × 10-14 1.457 0.182 4.29 (3.01-6.13) 1.13 × 10-14
 Braf 0.178 0.190 1.20 (0.82-1.73) 0.348 0.110 0.196 1.12 (0.76-1.64) 0.575
 Nuclear p300 -0.508 0.161 0.60 (0.44-0.83) 0.002 -0.525 0.169 0.59 (0.42-0.82) 0.002
 Cytoplasmic p300 0.049 0.163 1.05 (0.76-1.45) 0.764 0.091 0.171 1.10 (0.78-1.53) 0.595
  1. Coding of variables: AJCC was coded as 1 (stages I & II) and 2 (stages (III & IV). Braf and p300 expression was coded as 1 (low staining) and 2 (high staining).
  2. β: regression coefficient.
  3. Abbreviations: SE standard error of β, HR hazard ratio, CI confidence interval.