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Figure 1 | BMC Cancer

Figure 1

From: A combination of p300 and Braf expression in the diagnosis and prognosis of melanoma

Figure 1

Braf expression correlates with p300 expression in melanoma patients. (A) Negative correlation between Braf and nuclear p300 expression in melanoma patient biopsies. Melanomas which have high Braf expression have a significantly higher percentage of low nuclear p300 staining (p = 0.006, χ2 test). (B) Positive correlation between Braf and cytoplasmic p300 expression in melanoma patient biopsies. Melanomas which have high Braf expression also have a significantly higher percentage of high cytoplasmic p300 staining (p = 0.001, χ2 test). High Braf and high cytoplasmic p300 expression is significantly associated with AJCC progression (C) and tumor size (D), but not with ulceration status (E). p-values, 8.7×10-5, 0.001 & 0.119 respectively (χ2 test).

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