Figure 1
From: A combination of p300 and Braf expression in the diagnosis and prognosis of melanoma
Braf expression correlates with p300 expression in melanoma patients. (A) Negative correlation between Braf and nuclear p300 expression in melanoma patient biopsies. Melanomas which have high Braf expression have a significantly higher percentage of low nuclear p300 staining (p = 0.006, χ2 test). (B) Positive correlation between Braf and cytoplasmic p300 expression in melanoma patient biopsies. Melanomas which have high Braf expression also have a significantly higher percentage of high cytoplasmic p300 staining (p = 0.001, χ2 test). High Braf and high cytoplasmic p300 expression is significantly associated with AJCC progression (C) and tumor size (D), but not with ulceration status (E). p-values, 8.7×10-5, 0.001 & 0.119 respectively (χ2 test).