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Table 5 EORTC QLQ-H&N35 scales and TN stage

From: Influence of pain severity on the quality of life in patients with head and neck cancer before antineoplastic therapy

  T*   N**  
  T1 T2 T3 T4   N0 N+  
(n = 25) (n = 30) (n = 24) (n = 48) (n = 43) (n = 84)
EORTC QLQ –H&N35 Mean (SD) Mean (SD) Mean (SD) Mean (SD) p Mean (SD) Mean (SD) p
Pain 7.6 (13.5) 29.4 (26.5) 28.4 (28.2) 44.2 (34.5) <0.001 24.0 (29.2) 43.4 (30.7) <0.001
Swallowing 2.0 (6.0) 32.7 (32.8) 31.2 (33.5) 48.4 (33.3) <0.001 22.8 (32.0) 50.9 (30.1) <0.001
Senses problems 15.3 (33.6) 10.0 (21.2) 16.6 (28.2) 19 (35.4) 0.926 14.6 (30,6) 18.2 (31.2) 0.362
Speech problems 13.7 (25.7) 15.1 (22.5) 30.5 (33.4) 31.2 (31.2) 0.029 20.8 (27.9) 29.7 (32.2) 0.240
Trouble with social eating 2.0 (6.9) 19.1 (26.6) 25.6 (29.8) 34.0 (30.5) <0.001 14.4 (23.5) 38.5 (31.2) <0.001
Trouble with social contact 5.0 (7.2) 7.7 (14.0) 18.8 (20.4) 13.8 (20.1) 0.005 7.4 (10.7) 19.8 (24.2) 0.001
Less sexuality 12.0 (25.2) 16.1 (29.1) 29.1 (43.1) 30.5 (40.5) 0.211 14.0 (29.1) 41.0 (42.9) <0.001
Teeth 4.0 (14.6) 16.6 (34.7) 12.5 (29.1) 29.1 (42.1) 0.046 10.3 (26.8) 33.3 (43.6) 0.001
Opening mouth 1.3 (6.6) 10.0 (27.8) 19.4 (30.9) 36.1 (42.8) <0.001 15.4 (30.3) 28.6 (42.1) 0.112
Dry mouth 25.3 (38.8) 27.7 (37.2) 18.0 (36.7) 18.7 (34.3) 0.416 22.2 (36.7) 21.7 (35.5) 0.946
Sticky saliva 13.3 (27.2) 37.7 (40.8) 34.7 (45.5) 62.5 (41.6) <0.001 35.3 (40.5) 54.2 (46.5) 0.024
Coughing 20.0 (25.4) 26.6 (33.2) 22.2 (27.2) 22.9 (30.0) 0.955 21.4 (28.6) 26.3 (30.4) 0.337
Felt ill 8.0 (19.9) 11.1 (26.7) 23.6 (38.6) 27.7 (40.8) 0.125 13.8 (29.3) 29.4 (41.9) 0.042
Pain killers 28.0 (45.8) 70.0 (46.6) 83.3 (38.0) 77.0 (42.4) <0.001 60.7 (49.1) 79.0 (41.1) 0.038
Nutritional supplements 8.0 (27.6) 6.6 (25.3) 0 6.2 (24.4) 0.613 4.7 (21.4) 6.9 (25.7) 0.606
Feeding tube 0 0 0 0 - 0 0 -
Weight loss 4.0 (20.0) 40.0 (49.8) 54.1 (50.8) 70.8 (45.9) <0.001 34.5 (47.8) 72.0 (45.3) <0.001
Weight gain 28.0 (45.8) 23.3 (43.0) 8.3 (28.2) 6.2 (24.4) 0.035 16.6 (37.4) 11.6 (32.4) 0.453
  1. *Kruskal-Wallis test, **Mann Whitney test. Abbreviations: T, Tumor size; N, Lymph node involvement.