Figure 5
From: The effects of conjugate and light dose on photo-immunotherapy induced cytotoxicity
In vivo photoimmunotherapy in orthotopic breast tumors with a constant dose of 30 J/cm 2 delivered by 100 mA (CW), 400 mA (CW) and 1733 mA (PW) LED light. (A) Photon counts on bioluminescence images of tumors before and 1 day after LED irradiation. Photon counts of tumors in these three groups decreased around 60% (400 mA (CW), 60.1%; 100 mA (CW), 60.1%; 1733 mA (PW), 60.1%) 1 day after LED irradiation. (B) In vivo fluorescence (upper row) and bioluminescence imaging (lower row) of orthotopic breast tumors before and 1 day after Pan-IR700 mediated PIT.