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Figure 4 | BMC Cancer

Figure 4

From: Human Papillomavirus 16, 18, 31 and 45 viral load, integration and methylation status stratified by cervical disease stage

Figure 4

Methylation status distribution according to disease grade and genotype. Methylation profiles for (A) HPV16, (B) HPV18, (C) HPV31 and (D) HPV45 with each CpG site listed vertically across the top of each profile alongside their approximate genome position. The level of site-specific methylation is shaded according the scale bar from 0% - 100%. NT, a site did not exist in the given sample or failed to amplify. *, p < 0.05, **, p < 0.01, ***, p < 0.001 represent the significance level following a test for differences between normal and LG samples and HG samples (Mann Whitney U test).

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