Figure 1

Viral Load distribution according to disease grade and genotype. (A) Box and whisker plots of individual and overall viral load segregated by samples exhibiting normal (white), low grade (light grey) or high grade (dark grey) cytology. Boxes represent the median and IQR, while the whiskers encompass 1.5 times the IQR. Outliers are represented by a black dot. NS, p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001 (Mann Whitney U test between normal and LG or HG disease as indicated). (B) Receiver operator characteristic derived sensitivity and specificity plots for individual and overall viral load data. The line of equality represents an area under the curve (AUC) of 0.5.