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Figure 2 | BMC Cancer

Figure 2

From: Cell proliferation and apoptosis in rat mammary glands following combinational exposure to bisphenol A and genistein

Figure 2

Protein expressions in PND21 rats. Western blot analysis of cleaved Caspase-3, p21 and p-Akt from mammary gland extracts of PND21 rats exposed prepubertally via lactating dams treated with BPA and/or genistein, and SO. (A) Top panel depicts the Western blots of mammary gland proteins from SO controls (lanes 1, 5, 9, 13, 17 and 21), BPA (lanes 2, 6, 10, 14, 18 and 22), genistein (lanes 3, 7, 11, 15, 19 and 23) and BPA plus genistein (lanes 4, 8, 12, 16, 20 and 24) -treated groups with the appropriate antibodies shown on the left. For each treatment group, n = 6. (B) Densitometric values of Western blots from PND21 rats were reported as a percentage of controls ± SEM. *p ≤ 0.05 compared with controls; **p ≤ 0.05 compared with BPA; ***p ≤ 0.05 compared with genistein. No significant difference was detected for the house keeping protein GAPDH.

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