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Table 2 mRNA expression of ADHFE1 associated with CRC risk factors

From: Alcohol induces cell proliferation via hypermethylation of ADHFE1 in colorectal cancer cells

Characteristics

mRNA expression of ADHFE1

p-value

AdjN

T

Median (range)

Median (range)

Colorectal cancer

1.98 (±0.21)

1.14 (±0.22)

0.007

Age (years)

   

 ≤ 65

1.97 (±0.52)

1.54 (±0.41)

0.525

 > 65

1.94 (±0.29)

1.04 (±0.30)

0.034

Alcohol consumption

   

 Non-drinking

1.96 (±0.29)

1.21 (±0.30)

0.078

 Drinking

1.87 (±0.23)

0.94 (±0.23)

0.005

  1. Statistical significance is evaluated by analysis of variance (ANOVA). p-Values of < 0.05 are considered statistically significant.
  2. AdjN: Adjacent normal tissue; T: Colorectal cancer tissues.