Table 6 Association of co-expression of phosphorylated mTOR, S6RP and 4EBP1 with progression-free survival
Co-expression of phosphorylated targets | Median PFS (95% CI), months | P value |
|---|---|---|
p-mTOR (+)/p-S6RP (+) | Â | 0.001 |
 No | 3.7 (1.553-5.847) |  |
 Yes | 11.9 (5.559-18.241) |  |
p-mTOR (+)/p-4EBP1 (+) | Â | 0.006 |
 No | 3.7 (2.020-5.380) |  |
 Yes | 11.9 (2.734-21.066) |  |
p-S6RP (+)/p-4EBP1 (+) | Â | 0.032 |
 No | 3.7 (1.642-5.758) |  |
 Yes | 8.6 (2.183-15.017) |  |
p-mTOR (+)/p-S6RP (+)/p-4EBP1 (+) | Â | 0.006 |
 No | 3.7 (2.020-5.380) |  |
 Yes | 11.9 (2.734-21.066) |  |