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Table 1 Baseline demographic and clinical characteristics

From: Phosphorylation of mTOR and S6RP predicts the efficacy of everolimus in patients with metastatic renal cell carcinoma

Variables

Patients with tissue samples no. (%)

Patients without tissue samples no. (%)

Gender

  

 Male

14 (78%)

5 (71%)

 Female

4 (22%)

2 (29%)

Age (years)

  

 ≥ 60

2 (12%)

4 (57%)

 < 60

16 (88%)

3 (43%)

KPS score

  

 ≥ 90

11 (61%)

3 (43%)

 70-90

7 (39%)

4 (57%)

MSKCC risk factors

  

 0 (favorable)

8 (44%)

3 (43%)

 1-2 (intermediate)

8 (44%)

1 (14%)

 ≥ 3 (poor)

2 (12%)

3 (43%)

No. of metastatic sites

  

 1

8 (44%)

2 (29%)

 2

7 (39%)

5 (71%)

 ≥ 3

3 (17%)

0 (0%)

Prior therapy*

  

 First-line

18 (100%)

7 (100%)

 Second-line

8 (44%)

2 (29%)

 Third-line

1 (6%)

1 (14%)

Regimens of prior therapy*

  

 Sunitnib

7 (39%)

1 (14%)

 Sorafenib

10 (56%)

5 (71%)

 Axitinib

4 (22%)

1 (14%)

 Pazopanib

0 (0%)

1 (14%)

 Cytokines

3 (17%)

2 (29%)

 Chemotherapy

4 (4%)

0 (0%)

  1. *There were several patients who received multiple prior regimens of treatment.